Botox Peyronie's Treatment
Clinical trial into Botox Peyronie's treatment is currently taking place but the results are not yet available. Using Botox to treat men with Peyronie's disease is therefore not an approved Peyronie's treatment option.
What Is Botox?
Botox is the best know brand name for the neurotoxic protein called botulinum toxin. Botox is already approved for treating variety of medical conditions, like chronic migraines and certain muscle problems. It is however best known today for its use in the cosmetic industry.
Small amount of diluted botulinum toxin is injected into the muscle which reduces muscle activity in the area near the injection.
Scientific Studies For Botox Peyronie's Treatments
The Baylor College of Medicine (Houston) in collaboration with Allergan Inc. is currently conducting a study into using Botox as Peyronie's treatment. To my best knowledge, this is the only Peyronie's Botox study that is or has been performed.
There have been delays. According to ClinicalTrials.gov the estimated study completion date was January 2014 but is now January 2017 (last verified September 2015).
I have not been able to find reliable information about how Botox for Peyronie's is supposed to work. It though looks like men believe that Botox may inhibit scar formation.
Whether Botox may be able to reverse already present scarred tissue, or only prevent further scarring, is at this stage not clear to me.
Dr. Khera is the responsible party for this Peyronie's Botox study. His article in The Journal of Urology (Vol. 172, Issue 2, Pages 574-575) showed that men with urethral scars that received Botox injection were less likely of scar recurrence than those that did not receive Botox treatment.
The Peyronie's Botox study seems to be studying if the same applies to scars formed by Peyronie's disease.
The study includes injecting the Botox directly into the plaque in multiple injections (100 units of BOTOX® in 10 cc of preservative free normal saline). The result will be compared with placebo group, i.e. receiving only 10 cc of preservative free normal saline.
There is no indication when the results can be expected so I guess it is fair to assume that we will have to wait and see if Botox Peyronie's treatment will become a viable option for men with Peyronie's disease.
My Peyronie's Newsletter
Receive news and updates about Peyronie's disease. Simply sign up to my FREE Newsletter.